Glide Technologies Announces Successful Proof-of-Concept with Novel Ex


Sign up online today & collaborate

or click here to find out more

Glide Technologies Announces Successful Proof-of-Concept with Novel Exenatide Solid Dose Formulation


Oxford, UK – Glide Technologies, the development company focused on solid dose formulations of therapeutics and vaccines, today announced that the Company has successfully completed a pre-clinical proof-of-concept study with its novel solid dose formulation of exenatide, a GLP-1 agonist for the treatment of type 2 diabetes. Results from the pharmacokinetic study show that there was no statistical difference (p<0.05) between Glide’s solid dose formulation and the clinical dose of Byetta® (exenatide 10 mcg), the currently marketed liquid product.

Glide’s solid dose formulations are designed to be delivered using the Company’s self-administered, user-friendly, needle-free SDI® injector. The technology has multiple advantages over currently marketed liquid peptide products, which are needle administered and require cold chain logistics and refrigeration in the home. In particular, the technology has the potential to significantly improve patient compliance, which is important where self-administered injections are required, such as in diabetes.

The results follow previously announced successful proof-of-concept studies with Glide’s novel solid dose formulations of currently marketed liquid products Forteo®/Forsteo® (teriparatide) and Sandostatin® (octreotide). Consequently, Glide’s solid dose formulation technology has now achieved equivalence across a series of peptide products, demonstrating the flexibility of the platform to deliver this important class of therapeutics.

Dr Mark Carnegie-Brown, Glide’s CEO, commented, “These encouraging results follow positive equivalence data with Glide’s octreotide SDI® and teriparatide SDI® and clearly demonstrate the flexibility of our solid dose technology in delivering therapeutic peptides. The Glide SDI® has important advantages over current liquid products, particularly for self-administered treatments where patient-focused ease-of-use and compliance are key.”

CompanyGlide Technologies
Company Website


© Catalyst Innovation Portal 2019